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AVIXÉLA

AVIXÉLAAVIXÉLAAVIXÉLA
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WHO WE ARE
  • STRATEGY & MODEL
  • QUALITY & SAFETY STANDARD
  • EXECUTIVE COMMITTEE
  • HISTORY
SCIENCE & TECHNOLOGY
  • NANOBIOTECHNOLOGY
  • RESEARCH & DEVELOPMENT
  • OPEN INNOVATIONS
  • ANALYTICAL SERVICES
PRODUCTS & SERVICES
  • CONSUMER PRODUCTS
  • PROFESSIONAL PRODUCTS
  • FUNCTIONAL SYSTEMS
  • CUSTOM SYNTHESIS
COMMITMENTS
  • MANAGING WATER QUALITY
  • CONSERVING BIODIVERSITY
  • COLLABORATIVE OPERATIONS
  • EMPOWERING COMMUNITIES
CONTACT

AVIXÉLA

AVIXÉLAAVIXÉLAAVIXÉLA
GROUP
WHO WE ARE
  • STRATEGY & MODEL
  • QUALITY & SAFETY STANDARD
  • EXECUTIVE COMMITTEE
  • HISTORY
SCIENCE & TECHNOLOGY
  • NANOBIOTECHNOLOGY
  • RESEARCH & DEVELOPMENT
  • OPEN INNOVATIONS
  • ANALYTICAL SERVICES
PRODUCTS & SERVICES
  • CONSUMER PRODUCTS
  • PROFESSIONAL PRODUCTS
  • FUNCTIONAL SYSTEMS
  • CUSTOM SYNTHESIS
COMMITMENTS
  • MANAGING WATER QUALITY
  • CONSERVING BIODIVERSITY
  • COLLABORATIVE OPERATIONS
  • EMPOWERING COMMUNITIES
CONTACT
More
  • GROUP
  • WHO WE ARE
    • STRATEGY & MODEL
    • QUALITY & SAFETY STANDARD
    • EXECUTIVE COMMITTEE
    • HISTORY
  • SCIENCE & TECHNOLOGY
    • NANOBIOTECHNOLOGY
    • RESEARCH & DEVELOPMENT
    • OPEN INNOVATIONS
    • ANALYTICAL SERVICES
  • PRODUCTS & SERVICES
    • CONSUMER PRODUCTS
    • PROFESSIONAL PRODUCTS
    • FUNCTIONAL SYSTEMS
    • CUSTOM SYNTHESIS
  • COMMITMENTS
    • MANAGING WATER QUALITY
    • CONSERVING BIODIVERSITY
    • COLLABORATIVE OPERATIONS
    • EMPOWERING COMMUNITIES
  • CONTACT
  • GROUP
  • WHO WE ARE
    • STRATEGY & MODEL
    • QUALITY & SAFETY STANDARD
    • EXECUTIVE COMMITTEE
    • HISTORY
  • SCIENCE & TECHNOLOGY
    • NANOBIOTECHNOLOGY
    • RESEARCH & DEVELOPMENT
    • OPEN INNOVATIONS
    • ANALYTICAL SERVICES
  • PRODUCTS & SERVICES
    • CONSUMER PRODUCTS
    • PROFESSIONAL PRODUCTS
    • FUNCTIONAL SYSTEMS
    • CUSTOM SYNTHESIS
  • COMMITMENTS
    • MANAGING WATER QUALITY
    • CONSERVING BIODIVERSITY
    • COLLABORATIVE OPERATIONS
    • EMPOWERING COMMUNITIES
  • CONTACT

NATURAL INGRIDIENTS AND NATURAL ORIGIN OF ADVANCED MATERIALS

KEY ROLE OF INORGANIC ELEMENTS IN SKIN PHYSIOLOGY

Natural ingredients are used to produce cosmetic products that are environmentally friendly instead of products that can harm the skin. Skin health relies heavily on the proper functioning of key processes, including bioenergetics, redox balance, barrier function, and dermal remodeling. These vital processes are significantly influenced by the availability and balance of essential natural and natural origin mineral elements. Adequate levels and proper distribution of inorganic ions within the skin are crucial for supporting skin regeneration and mitigating the effects of aging.  


Skin is the body's largest organ, covering an area of approximately two square meters and constituting a significant portion of body weight. It serves as the dynamic interface between the body and external environment. The mineral composition of human skin and its appendages differs significantly from the overall mineral composition of the human body. 


The elementary mechanisms governing cell and tissue function employ the same mineral elements in the skin as in the other organs. However, the particular role of the epidermis as the outside-in and inside-out permeability barrier and the protective role of the entire integument permanently exposed to environmental aggressions require specific local arrangements. While life on Earth is primarily carbon-based, it crucially depends on a diverse array of elements found within the planet's crust. These elements, beyond carbon, play indispensable roles in the functioning of living organisms.


AviXéla is dedicated to supporting the entire production lifecycle of custom inorganic nanomaterials. We are committed to continuous improvement in our manufacturing processes, expanding our capabilities in organic materials manufacture and analytical expertise. Our goal is to provide our customers with access to high-quality materials at competitive prices. 

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Mineral and trace elements in human skin, quantity per whole body weight

  % Whole Body Weight                                                    Chemical Composition

Bulk organic elements (95%)                                                              C, O, H, N

Macroelements (<5%)                                                      Na, K, Mg, Ca, P, S, Cl

Oligoelements (<0.1%)                                                   Cu, Zn, Se, Mn, Fe, Mo 

Co-Oligoelements (<0.01%)                                           F, I, Sn                            

Trace elements found on the skin surface                                 Ag, Au, As, B, Cr, Ni, St, V, Al, Zr, Hg, Si

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AVIXÉLA'S UNIQUE NANOMATERIALS FOR SKIN CARE

  • (Ag) SILVER 
  • (Al) ALUMINIUM
  • (Au) GOLD
  • (Cu) COPPER
  • (Ni) NICKEL
  • (Pl) PALLADIUM
  • (Pt) PLATINUM
  • (Ti) TITANIUM
  • (Zn) ZINC

EXPLORE OUR SERVICES

Our nanomaterials line includes inorganic particles and colloid systems ranging size from less than 1 nm to 100 nm diameter with variety of surface stabilization.  The sample size of nanoparticles and concentration may be customized as required as high as 70 volume percent. 

EXPLORE NANOMATERIAL PROPERTY GUIDE

AVIXÉLA nanoMATERIALS APPLICATIONS

RANGE OF MATERIALS

QUALITY ANALYSIS AND SCALE-UP STRATEGY

MEDIA FORMATS AND APPLICATIONS

 Deep capacity of advanced nanomaterials manufacture, particularly from gold, platinum, palladium, silver, and copper. 

MEDIA FORMATS AND APPLICATIONS

QUALITY ANALYSIS AND SCALE-UP STRATEGY

MEDIA FORMATS AND APPLICATIONS

Providing access to a different nanomaterial formats including dispersions, colloids, and functional systems 

QUALITY ANALYSIS AND SCALE-UP STRATEGY

QUALITY ANALYSIS AND SCALE-UP STRATEGY

QUALITY ANALYSIS AND SCALE-UP STRATEGY

Quality analysis of primary natural ingredients, followed by analysis of nanomaterials chemico-physical properties. 

MONODISPERSION AND CONCENTRATION

QUALITY ANALYSIS AND SCALE-UP STRATEGY

QUALITY ANALYSIS AND SCALE-UP STRATEGY

Creating stable and concentrated dispersions in aqueous, organic, and proprietary customer fluids. 

DISCOVER OUR UNIQUE NANOCOLLOID SYSTEMS

GOLD

SILVER

SILVER

AVIXELA .9999 FINE GOLD NANOCOLLOID SYSTEM OBTAINED WITHOUT CHEMICAL STABILIZATION IN HPLC WATER

SILVER

SILVER

SILVER

AVIXELA .9999 FINE SILVER NANOCOLLOID SYSTEM OBTAINED WITHOUT CHEMICAL STABILIZATION IN HPLC WATER

COPPER

SILVER

COPPER

AVIXELA .9999 FINE COPPER NANOCOLLOID SYSTEM OBTAINED WITHOUT CHEMICAL STABILIZATION IN HPLC WATER

WHY US?

  • Alternate cost-effective manufacturing of customized advanced nanomaterials through cutting-edge plasmonic and adaptive acoustic reproducible techniques, presenting advantages of green technology.   
  • Plasma syntheses over variable interface aerosol and liquid systems with flexibility of using reducing agents and unnecessary organic solvents.  
  • Uniformity and scalability of inorganic spherical nanoparticles and nanoclusters with unique homogeneity less than 1 nm and between 1 and 100 nm in size. 
  • Robust processing to scale one-pot concentrated nanomaterials more than 70 OD from prototype to high-volume production. 
  • Effective self-assembling polymers and solvent born spontaneous nanocoating through capping by functionalized nanomaterials.    

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THE ANATHOMY OF LIQUID-BASED SKIN FORMULATIONS

Water constitutes 60-70% of the human body, serving as the essential medium for biochemical reactions. It facilitates the interaction of organic and inorganic molecules within our organisms. Crucial life functions, such as nutrient absorption, tissue growth, and waste removal, rely heavily on water. In ionized water form, minerals get access to cells and tissues and become integrated into the living matter. 


Water is a primary ingredient that makes up a significant portion of the skin care formulations, allowing for lightweight and breathable texture. The exact percentage of water is not readily available to the public and cannot be found on the product's ingredient list.  While the exact water content of skin foundations varies depending on the specific product, most of them are considered water-based.


Cosmetic formulations have significantly advanced in recent years, driven by a deeper understanding of skin science. Key physicochemical properties, such as density, refractive index, oxidation state, and vibrational frequency, play crucial roles in determining the effectiveness of cosmetic ingredients. These properties guide the formulation of superior emollients and day creams, optimizing their performance and benefits for the skin. 


The physicochemical properties of emollients, such as density, refractive index, and oxidation state, significantly influence their ability to effectively cover and moisturize the skin. These properties impact how the emollient spreads, absorbs, and interacts with the skin's natural barrier. Emollients are a crucial component of many cosmetic formulations, typically constituting 5-30% of oil-in-water (O/W) emulsions. After water, they represent the second-largest group of ingredients in these formulations.


Cosmetic emulsions consist of two immiscible phases: an oil phase and an aqueous phase. Emulsifiers, acting as surfactants, stabilize this mixture by reducing interfacial tension. They can be classified as O/W emulsions where oil droplets are dispersed within a continuous water phase, and W/O emulsions where water droplets are dispersed within a continuous oil phase. These emulsions incorporate various components, including hydrophilic phase,  hydrophobic phase,  emulsifiers, functional additives, preservatives, fragrances. 


The choice of ingredients and their specific proportions significantly influence the stability, texture, and performance of the final emulsion. While W/O emulsions can provide a protective barrier, their ability to directly hydrate the skin may be limited compared to O/W emulsions, which can more readily deliver water to the skin. 

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AviXéla PULSE PLASMA-ACTIVATED WATER TECHNOLOGY

RANGE OF LIQUIDS

QUALITY ANALYSIS AND SCALE UP CONSIDERATIONS

PLASMA DISCHARGE IN THE AGUEOUS SOLUTION

 Deep capacity of plasma treatment of organic and inorganic liduids. 

PLASMA DISCHARGE IN THE AGUEOUS SOLUTION

QUALITY ANALYSIS AND SCALE UP CONSIDERATIONS

PLASMA DISCHARGE IN THE AGUEOUS SOLUTION

Precise control of various electrode configurations of cold aerosol and liquid dielectric barrier discharge (DBD) systems,  such as spark or glow. 

PLASMA DISCHARGE IN THE GROWTH MEDIUM

QUALITY ANALYSIS AND SCALE UP CONSIDERATIONS

QUALITY ANALYSIS AND SCALE UP CONSIDERATIONS

Precise control of various electrode configurations of cold atmospheric plasma (CAP) jet systems. 

QUALITY ANALYSIS AND SCALE UP CONSIDERATIONS

QUALITY ANALYSIS AND SCALE UP CONSIDERATIONS

QUALITY ANALYSIS AND SCALE UP CONSIDERATIONS

Analysis of chemico-physical and antimicrobial properties of PAW and customized liquids.

WHY plasma-activated water?

Plasma, as the fourth state of matter, is an ionized gas containing excited and neutral atoms, electrons, free radicals, ions, and high-energy photons. When plasma interacts with a liquid, particularly water, it creates plasma-activated water (PAW).  Cold plasma treatment has demonstrated efficacy in disrupting bacterial biofilms, reducing antibiotic contaminants, and degrading complex organic pollutants, making it an innovative and eco-friendly alternative to conventional methods. 


PAW's role in cosmetology related to support of a healthy skin barrier, enhancing hydration through improved water penetration, and management of skin conditions. It's used in conjunction with other hydrating ingredients to improve overall skin health, especially in the context of anti-aging skincare: 


  • Antioxidant Effects: PAW contains reactive oxygen and nitrogen species, which, at controlled levels, can act as antioxidants that neutralize free radicals, unstable molecules damaging cells and DNA over the aging. 
  • Improved Skin Barrier Function: PAW improve skin barrier function by influencing the production of lipids and proteins essential for skin barrier integrity. A compromised skin barrier can accelerate aging by leading to moisture loss and increased vulnerability to environmental damage. 
  • Improving Skin Hydration: PAW might enhance skin hydration by altering the structure of water and improving its penetration into the skin, leading to better absorption of moisturizing ingredients in cosmetic products.
  • Enhanced Collagen Production:  PAW stimulate collagen production, potentially improving skin firmness and reducing wrinkles.
  • Anti-inflammatory Properties: PAW's has anti-inflammatory effects that could help to slow down the aging process. 
  • Addressing Skin Conditions that Contribute to Dehydration: PAW's antimicrobial properties could help to manage acne, eczema, and skin cancer indirectly improving skin hydration.  


Apart from cosmetology and skin care, PAW can also optimise intact skin and facilitate transdermal drug delivery with controllable safety and minimal side effects. Nonetheless, several challenges remain to be fully addressed before each specified application this unique therapy. 

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PLASMA-ACTIVATED WATER ANTIMICROBIAL EFFICIENCY

 MICROORGANISMS AFFECTED     

 

Methicillin-susceptible S. aureus

Methicillin-resistant Staphylococcus aureus

 E. coli O104 

 E. coli O157 

 Candida albicans and Penicillium Chrysogenum 

 Salmonella enterica serovar Enteritidis 

 Pseudomonas deceptionensis 

 Enterobacter aerogenes 

 S. cerevisiae 

 Staphylococcus aureus 

 Shewanella putrefaciens

Aspergillus niger A32 

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INGREDIENTS WE DO NOT USE IN OUR PRODUCTS

  • 1,4 – Dioxane**
  • Acetaldehyde
  • Acetonitrile
  • Acrylamide**
  • Benzene**
  • Bisphenol A*
  • Butylated hydroxyanisole (BHA) 
  • Butoxyethanol
  • Methylene chloride
  • Diethanolamine (DEA) and diethanolamine (DEA) complexes**
  • Formaldehyde**
  • Hydroquinone
  • Heavy metals**
  • Plastic microbeads*
  • Alkylphenols: nonylphenols (NP) and ethoxylated nonylphenols (NPEs)
  • Phtalates**
  • Toluene**
  • Triclocarban
  • Triclosan
  • Glyoxilic acid


* These ingredients are prohibited by regulation, you will not find them in our products. 

** We do not use these ingredients in our products. 

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  • QUALITY & SAFETY STANDARD

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