TIME IS OUT OF THE ESSENCE
TIME IS OUT OF THE ESSENCE
AviXéla research is dedicated to development of advanced formulations using high-quality, sustainable ingredients and natural ingredients nanomaterials. We are committed to preserving biodiversity and ensuring the safety of our customers.
Nanotechnology is driving significant advancements in cosmetic, cosmeceuticals, and pharmaceutical formulations and delivery systems. Its application in nanocosmetics and nanocosmeceuticals has shown promise for improving product efficacy and consumer satisfaction across various areas, including skin, hair, nails, lips, and teeth. The incorporation of nanomaterials has demonstrably contributed to the growth of both the pharmaceutical and cosmetic markets worldwide.
Nanotechnology offers significant advantages in cosmeceutical formulations, including prolonged action, enhanced bioavailability, and improved aesthetics. Compared to traditional cosmeceuticals, nano-based products benefit from the unique properties of nanomaterials, such as their small size and high surface-to-volume ratio, making them effective delivery vehicles. These nanoparticles enhance various product attributes without altering the core properties of the cosmeceutical itself. Specifically, they improve UV protection, skin penetration, color and fragrance release, finish quality, anti-aging effects.
These improvements are achieved through mechanisms like controlled release, targeted delivery, improved biocompatibility, and enhanced drug-loading capacity, ultimately leading to more effective and desirable cosmeceutical products.
Inorganic nanocolloids and nanoparticles have unique beneficial properties that can be leveraged across several applications, including functional coating, catalysts, additives, conductive inks, antimicrobial, and antitumorogenic. Specifically, the size of inorganic nanomaterials ranges from 1 to 100 nm that are similar to cellular components and microorganisms can be employed as innovative tools in biomedical therapy, diagnostics, and drug delivery. Most inorganic nanomaterials display customizable morphology, high biocompatibility, reliable functionalization, and prolonged circulation in the bloodstream.
AviXéla employs its proprietary platform to optimize and design custom nanomaterials, working with an expansive list of natural ingredients, including inorganic nanoparticles that are more hydrophilic, biocompatible, safer, and exceptionally more stable as compared to polymeric and organic derived nanoparticles.
Nanoparticle-based delivery systems, which can overcome the challenges associated with poor aqueous solubility and other harmful side effects of drugs, display potent applications in cosmetics and dermatology. Formulations with functional systems can create skincare products that are effective, stable, and safe for consumers, including emulsions.
Emulsions, being mixtures of oil and water, can effectively deliver a wide range of active ingredients in skincare. The most important functional systems are: delivery, emulsification, preservation, texturizing, and active ingridient. These systems deliver the intended benefits to the skin, such as hydration, anti-aging, or sun protection.
Examples include:
Hydrophobically modified nanoparticles, particularly gold, are easily dispersed in the oil phase of the emulsion due to the surface compatibility, allowing them to readily mix and distribute within the oil droplets. This compatibility helps prevent the gold nanoparticles from aggregating or separating from the oil phase, leading to a more stable and homogenous emulsion. The simplified encapsulation process of incorporating these hydrophobically modified gold nanoparticles into the oil droplets of the emulsion becomes straightforward, as they naturally tend to associate with the oil phase.
PRECISION CONTROL OVER ADVANCED MATERIALS PROPERTIES AND TECHNICAL ATTRIBUTES TO MAXIMAZE PERFORMANCE
PROVEN ABILITY TO SCALE UP ADVANCED MATERIALS AND FUNCTIONAL SYSTEMS COMPARE TO THEIR COUNTERPARTS
INFRASTRUCTURE DESIGNED TO AQUIRE THE COST-EFFECTIVE PRODUCTION AT PILOT AND INDUSTRIAL SCALE VOLUMES
Nanocomposites in cosmetics refer to the incorporation of nanomaterials into cosmetic formulations to enhance their properties and performance. These nanomaterials, typically ranging in size from 1 to 100 nanometers, can be organic, inorganic, or a combination of both. Our team inspire change that is focused on production of unique Gold nanoparticles, Gold nanofluids, and multifunctional nanocomposite systems, which enable to play a crucial role in cosmetics and biomedical applications. The Gold nanomaterials enable to:
1. Stabilizing Emulsions, acting as pickering emulsifiers, which are solid particles that stabilize emulsions by adsorbing at the oil-water interface, especially under harsh conditions like high temperatures or extreme pH levels.This creates a physical barrier that prevents the droplets from coalescing and the emulsion from separating.
2. Enhancing Delivery of Active Ingredients, acting as carrier systems that encapsulate or attach active ingredients, such as drugs or cosmetic actives, and deliver them to target sites within the skin. Gold nanoparticles improved penetration through the skin barrier and providing unique optical properties due to the surface plasmon resonance, which can enhance the visual appeal of cosmetic products.
3. Providing Additional Functionality through antioxidant properties, protecting the skin from damage caused by free radicals, and demonstrating antimicrobial properties, which could be beneficial in certain cosmetic formulations.
Overall, gold nanoparticles offer a range of potential benefits in emulsions, from enhancing stability and delivery to providing unique optical and functional properties.
The common laboratory-scale synthesis methods, which introduce the nanomaterials additives to already existing formulations of fluids available, requires the understanding of nanofluids behavior and multilevel infusion/incorporation technologies. Our plasma excitation method of controlled production and addition of inorganic nanoparticles without chemical contamination can become one of the advanced dispersion methods. We develop nanomaterials sunthesis methods that are reusable, convenient, and cost aware.
AviXéla focuses on the development of different plasmonic biosensing materials with improved performance based on their unique properties, such as high surface area-to-volume ratio, that facilitate the biochemical analyte capturing and signal amplification, necessary for localized surface plasmon resonance, fluorescence enhancement, plasmon and colorimetry quenching. Using our alternate plasma scale treatment, we can achieve the reduction, deposition, and decomposition of active components, different types of nucleation, and crystal growth of catalytic materials. Compared to the conventional thermal methods, this plasma process produces smaller particle sizes over enhanced activity and stability.
Due to their unique properties, such as the size, optical, biodegradable, low-toxicity, biocompatibility, and highly catalytic features, our steadily developed spherical nanoparticles applicable for various bio-functionalization and represent a rapidly growing part of our internal research and development. In order to prevent rapid aggregation, oxidation, and other problems, we evaluate their subsequent utilization and adequate surface modification with organic and inorganic compounds.
We are in the process to utilize spherical gold nanoparticles, specifically conjugated for in vitro applications via a proprietary covalent polymer bridge to the PEG, alkyne, amine, azide, biotin, carboxyl, hydroxyl, methyl, maleimide, neutravidin, heparin, streptavidin, GSH, Protein A and G, galactose, thiol, and secondary antibodies. These nanoproducts are resistant to spontaneous aggregation, temperature, salt, pH, and possess exceptional loading capability that are critical for diagnostics and imaging in adverse environments.
We keep all candidate materials, coming out of our company, confidential to the specific project they were designed for. During discovery, we will discuss primary project goals and create the path of testing commercially available options, optimizing materials to meet their specific product requirements. Quality and consistency during production is paramount. Our specialized in-house team will ensure both timely and accurate results, quality, cost, and timeline parameters.
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